(AP) — The most anticipated matchup of the Week 6 NFL schedule became a blowout before halftime.

The Tampa Bay Buccaneers spotted the Green Bay Packers a 10-0 lead before storming toward a 38-10 victory. The Bucs took the lead with help from Aaron Rodgers, whose first two interceptions of the season led to two touchdowns for Tampa Bay.

Cornerback Jamel Dean broke on Rodgers’ sideline throw intended for Davante Adams and returned the pick 32 yards to get the Bucs rolling. Safety Mike Edwards returned a second interception to the Green Bay 2 to set up Ronald Jones’ rushing TD on the next play, giving the Buccaneers a 14-10 lead.

Neither quarterback threw for more than 170 yards in a clash of the very best at their position. Tom Brady threw for 166 yards and two TDs without an interception before giving way to Blaine Gabbert.

The Buccaneers improved to 4-2 and dropped the Packers to 4-1.

---If the Steelers were trying to make a statement on Sunday, it was loud and clear as they crushed the Browns by a 38-7 margin.

James Conner ran for 101 yards and a touchdown in the Steelers’ 17th consecutive victory over the Browns at Heinz Field. Ben Roethlisberger added 162 yards passing and a touchdown, and Chase Claypool ran for a score while grabbing four passes for 74 yards.

The Steelers sacked aching Baker Mayfield four times, picked him off twice and chased him late in the third quarter with the game out of reach. The NFL’s top rushing offense managed 75 yards on the ground, 113 below its season average.

The 5-0 Steelers still lead the AFC North by a half-game over Baltimore. The Browns are third in the division at 4-2 after ending a four-game winning streak.

Elsewhere on the NFL schedule:

— Lamar Jackson threw for a touchdown and ran for a score while the Ravens were building a 24-6 lead in a 30-28 victory at Philadelphia. Jackson ran for a 37-yard TD and had 108 yards on the ground to go with his 186 yards passing. Carson Wentz tossed two TD passes, but he was sacked six times and was stopped on a two-point conversion attempt that would have tied the game with 1:55 to play.

— The Titans are 5-0 after Derrick Henry took a direct snap and ran 5 yards for a touchdown 3:30 into overtime to end a 42-36 comeback win over the Texans. Deshaun Watson’s fourth TD pass put Houston up 36-29 with 1:50 left in regulation, but a failed 2-point conversion attempt gave Tennessee a chance to force overtime. Ryan Tannehill marched the Titans 76 yards on the ensuing series and found A.J. Brown on a 6-yard TD pass with 4 seconds left in the fourth quarter. Houston is 1-5.

— Jimmy Garoppolo threw three TD passes while the 49ers were building a 21-6 lead in the first half of a 24-16 victory against the Rams. Garoppolo was unable to keep up his fast start to the game but still finished 23 for 33 for 268 yards a week after being pulled from a game. Jason Verrett’s first interception in more than four years ended the Rams’ final threat to tie the game. Los Angeles is 4-2 and the 49ers are 3-3.

— Chicago’s defense forced three turnovers and sacked Teddy Bridgewater four times in a 23-16 verdict over the Panthers. Nick Foles threw for one touchdown and ran for another as the 5-1 Bears improved to 3-0 on the road for the first time since their 2006 NFC championship season. Carolina had a failed fourth down play and an interception on its last two series to fall to 3-3.

— The Colts trailed 21-0 until Philip Rivers tossed three touchdown passes, including the go-ahead score early in the fourth quarter of a 31-27 triumph against Cincinnati. Rivers wound up 29 of 44 with 371 yards as Indianapolis tied the biggest regular-season comeback in franchise history. Giovanni Bernard, Joe Burrow and Joe Mixon had short scoring runs before the 1-4-1 Bengals, who blew a lead of at least 21 points for the fifth time ever.

— Brandon McManus drilled six field goals and linebacker Malik Reed came up with a big sack late to help the Broncos hold on for an 18-12 win over the Patriots. Drew Lock finished 10 of 24 for 189 yards in his first start since injuring his shoulder in Denver’s Week 2 loss to Pittsburgh. The Broncos’ defense came up with two interceptions and a fumble recovery after entering the game with just two takeaways. Both teams are 2-3 after finally playing a game that was twice postponed due to positive coronavirus tests.

— Ryan Fitzpatrick threw for three touchdowns and the Dolphins posted their first shutout in six years by downing the Jets, 24-0. The Dolphins didn’t allow a third-down conversion until the fourth quarter and reached .500 for the first time under second-year coach Brian Flores. The game was so lopsided that Miami rookie Tua Tagovailoa (TOO’-uh tuhng-ah-vy-LOH’-ah) made his NFL debut in mop-up duty with 2:27 left. The Jets are 0-6 for the first time in 24 years.

— Julio Jones returned from injury to catch two of Matt Ryan’s four touchdown passes in the Falcons’ 40-23 thrashing of the Vikings. Ryan completed 30 of 40 passes for 371 yards as Atlanta won its first game under interim coach Raheem Morris. Kirk Cousins threw three interceptions in the first half for the first time in his career, leading to 17 Falcons points. Each team is 1-5.

— The Lions rolled to a 34-16 win against the Jaguars as rookie D’Andre Swift ran for a season-high 116 yards and two touchdowns. Matthew Stafford got an elusive TD pass against the only team he hadn’t thrown one against in 12 NFL seasons. Kenny Golladay finished with four receptions for 105 yards, marking the first time since 2013 that the Lions had a 100-yard rusher and a 100-yard receiver in the same game. Both teams are 2-3.

— The Giants have their first victory under coach Joe Judge after Tae Crowder scooped up a fumble and ran 43 yards for a touchdown with 3:28 left in a 20-19 win over Washington. Kyle Allen hit Cam Simms for a 22-yard TD in the final minute, but Allen threw an incompletion on the conversion attempt after Washington coach Ron Rivera elected to go for the win. Daniel Jones threw a 23-yard touchdown pass to Darius Slayton and Graham Gano kicked two field goals as the 1-5 Giants dropped Washington to 1-5.